Fluvoxamine Maleate Fluvoxamine is a selective serotonin (5-HT) reuptake inhibitor (SSRI) that exhibits antidepressant, anti-inflammatory, cardioprotective, and antioxidative activities. Fluvoxamine inhibits the serotonin transporter (SERT) and also activates pre-synaptic 5-HT3…
Fluvastatin Sodium Fluvastatin is an inhibitor of HMG-CoA reductase that is clinically used to lower cholesterol and treat cardiovascular disease. Fluvastatin exhibits anti-hyperlipidemic, anti-fibrotic, cardioprotective, antiviral, antithrombotic, antioxidative, vasorelaxant, anti-atherosclerotic,…
Flutriafol Flutriafol is a triazole antifungal pesticide; it acts as a demethylation inhibitor, preventing sterol biosynthesis and disrupting membrane function. Flutriafol may also exhibit neuromodulatory and antioxidative activity in vivo,…
Fluticasone Propionate Fluticasone is an agonist at β2-adrenergic receptors that is clinically used to treat asthma and COPD; it exhibits anti-inflammatory, vasodilatory, anti-asthma, and anti-allergic activities. In airway epithelial cells,…
Flutamide Flutamide is a non-steroidal inhibitor of the androgen receptor; it exhibits anticancer chemotherapeutic, anti-inflammatory, and anti-androgenic activities. Flutamide is clinically used to treat prostate cancer and polycystic ovary syndrome.…
Flurbiprofen Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat arthritis. Flurbiprofen is a non-selective inhibitor of COX-1 and COX-2 that exhibits analgesic, anti-inflammatory, neuroprotective, anti-metastatic,…
Flupirtine Maleate Flupirtine maleate is an agonist at voltage-gated KCNQ/Kv7 K+ channels; opening of these channels on neurons facilitates M-current generation and decreases axonal excitability. In addition to its modulation…
Fluphenazine Hydrochloride Fluphenazine is a typical piperazine antipsychotic that is clinically used to treat schizophrenia, bipolar disorder, and dementia. Fluphenazine acts as an antagonist at D2 receptors. Fluphenazine also exhibits…
Fluoxetine Hydrochloride Fluoxetine is an SSRI most often used to treat mood or psychiatric disorders such as depression, obsessive compulsive disorder, bulimia nervosa, panic disorder, and PTSD. Fluoxetine inhibits 5-HT…
Fluocinolone Acetonide Fluocinolone is a synthetic hydrocortisone derivative that exhibits anti-inflammatory and anti-pruritic activities. Fluocinolone is a corticosteroid that is clinically used to treat ocular inflammation. In dental pulp cells,…