We discovered that SIRS-induced activation of NF-B in both MLNs and ileum mucosa was reversed by pretreatment with CO in a dose-dependent manner with statistical importance at doses of thirteen and 26 mg/kg (Fig. 2)
The distal ileum fixed in ten% neutral buffered formalin was embedded in paraffin, sectioned at 5 m, and stained with hematoxylin and eosin to assess the destruction of the villus…